Description

Topicaine CAS NO 76-91-5 is a high-purity pharmaceutical intermediate and fine chemical, chemically known as 2-(Diethylamino)ethyl 4-aminobenzoate hydrochloride. This compound is valued for its role as a key precursor in the synthesis of specialized local anesthetic agents and other bioactive molecules. It is essential for manufacturers in the pharmaceutical, research, and fine chemical sectors requiring reliable, high-quality building blocks for complex syntheses.

Application

• Pharmaceutical Synthesis: Primary use as a critical intermediate in the production of local anesthetic drugs and related pharmaceutical compounds.
• Research & Development: Serves as a building block in medicinal chemistry for developing new anesthetic and analgesic agents.
• Fine Chemical Manufacturing: Used in the synthesis of specialty chemicals requiring the 4-aminobenzoate ester moiety.
• Biochemical Research: Employed in studies investigating the mechanism of action of sodium channel blockers.
• Reference Standard: Can be utilized as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical labs.

Basic Information

Item	Details
Product Name	Topicaine
CAS No.	76-91-5
Molecular Formula	C13H21ClN2O2
Molecular Weight	272.77 g/mol
Synonyms	2-(Diethylamino)ethyl 4-aminobenzoate hydrochloride; Procaine Hydrochloride Impurity A; Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester, hydrochloride; 4-Aminobenzoic acid 2-(diethylamino)ethyl ester hydrochloride; Diethylaminoethyl p-aminobenzoate hydrochloride; Ethocaine hydrochloride (related); Contact for details on additional trade names.
EINECS	200-990-1

Quality Control

Our Topicaine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.