Description

5-(2-Propenyl)-2'-Deoxyuridine is a modified nucleoside analog, a key building block in medicinal chemistry and life science research. This compound is valued for its role as a versatile intermediate in the synthesis of novel antiviral and anticancer agents, particularly in the development of targeted prodrugs and oligonucleotide therapeutics. It is primarily utilized by pharmaceutical R&D departments, biotechnology firms, and academic research institutions focused on nucleoside chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Prodrug Development: Used to create targeted prodrugs designed for selective activation in specific tissues or cells.
• Oligonucleotide Synthesis: Serves as a modified building block for incorporating unique functionalities into DNA/RNA sequences for therapeutic or diagnostic applications.
• Biochemical Research: Employed in studies investigating enzyme mechanisms, such as thymidine kinase, and DNA metabolism.
• Antisense & Gene Therapy Research: Utilized in the development of modified oligonucleotides for gene silencing and therapeutic gene editing platforms.
• Labeling & Probe Development: The propenyl side chain provides a handle for further chemical conjugation with fluorescent tags or other reporter molecules.

Basic Information

Product Name	5-(2-Propenyl)-2'-Deoxyuridine
CAS No.	73-39-2
Molecular Formula	C₁₂H₁₆N₂O₅
Molecular Weight	268.26 g/mol
Synonyms	5-Allyl-2'-deoxyuridine; 5-Allyl-dU; 5-(2-Propen-1-yl)-2'-deoxyuridine; 5-Allyldeoxyuridine; 5-Prop-2-en-1-yl-2'-deoxyuridine; 2'-Deoxy-5-(2-propen-1-yl)uridine; dU-allyl; Allyl-dU
EINECS	Contact for details

Quality Control

Our 5-(2-Propenyl)-2'-Deoxyuridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.