Description

11-Dehydrocorticosterone is a naturally occurring steroid hormone and a key intermediate in the biosynthesis of corticosteroids. This compound is of significant value in pharmaceutical research and development, serving as a crucial precursor for synthesizing more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in steroid chemistry, metabolic studies, and the production of reference standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of corticosteroid drugs, including anti-inflammatory and immunosuppressive agents.
• Biochemical Research: Used as a reference standard and reagent in studies investigating adrenal cortex function, steroidogenesis, and metabolic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control (QC) and method development in pharmaceutical and clinical laboratories.
• Fine Chemical Synthesis: Employed in organic synthesis for the preparation of novel steroid derivatives with potential therapeutic applications.
• Metabolite Studies: Utilized in research to understand the metabolism and biological activity of endogenous corticosteroids.

Basic Information

Product Name	11-Dehydrocorticosterone
CAS No.	72-23-1
Molecular Formula	C21H28O4
Molecular Weight	344.45 g/mol
Synonyms	11-Dehydrocorticosterone; 21-Hydroxypregn-4-ene-3,11,20-trione; 17-Deoxycortisone; Kendall's Compound A; Reichstein's Substance D; 11-Oxocorticosterone; 4-Pregnene-21-ol-3,11,20-trione
EINECS	200-773-2

Quality Control

Our 11-Dehydrocorticosterone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can supply material compliant with various pharmacopeial standards upon request, ensuring it meets the rigorous demands of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term stability, storage at 2-8°C is recommended. The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.