Description

5'-Chloro-5'-Deoxyadenosine Hydrate, 97% is a modified nucleoside analog, serving as a crucial building block in synthetic organic chemistry and pharmaceutical research. This compound is valued for its role as a key intermediate in the synthesis of novel antiviral and anticancer agents, particularly in the development of nucleotide-based prodrugs. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity intermediates for advanced drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and DNA/RNA synthesis.
• Prodrug Development: Serves as a precursor in the design and synthesis of nucleotide prodrugs to enhance drug delivery and efficacy.
• Antiviral Agent Synthesis: Critical intermediate in the preparation of experimental compounds targeting viral polymerases.
• Labeled Compound Synthesis: Used as a starting material for the preparation of isotopically labeled (e.g., deuterated, C13) nucleosides for metabolic tracing studies.
• Medicinal Chemistry: Building block for creating novel chemical libraries for high-throughput screening against various biological targets.

Basic Information

Product Name	5'-Chloro-5'-Deoxyadenosine Hydrate, 97%
CAS No.	698999-09-6
Molecular Formula	C10H12ClN5O3 · xH2O
Molecular Weight	285.69 g/mol (Anhydrous basis)
Synonyms	5'-Chloro-5'-deoxyadenosine hydrate; 9-[(5-Chloro-5-deoxy-β-D-ribofuranosyl)]adenine hydrate; 5'-Chloro-5'-deoxyadenosine monohydrate; 5'-Cl-5'-dA hydrate; Adenosine, 5'-chloro-5'-deoxy-, hydrate; 5'-Chloro-5'-deoxyadenosine (hydrate); 5'-Chloro-5'-deoxy-adenosine.
EINECS	Contact for details

Quality Control

Our 5'-Chloro-5'-Deoxyadenosine Hydrate, 97% is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods (NMR, IR), to ensure it meets the specified 97% minimum purity. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.