Description

4-Bromo-3-Fluorobenzoyl Chloride is a high-purity aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functional groups, which enable efficient and selective coupling reactions to construct complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules containing benzamide or benzophenone scaffolds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides that require halogenated aromatic components.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating halogenated aromatic cores in electronic and display chemicals.
• Polymer Chemistry: Employed as a monomer or modifying agent to introduce bromo- and fluoro-substituted benzoate groups into polymer chains for enhanced properties.
• Peptide Coupling & Bioconjugation: Acts as an efficient acylating agent for coupling reactions in peptide synthesis and bioconjugate chemistry.
• Organic Synthesis Reagent: A versatile reagent for Friedel-Crafts acylation, nucleophilic substitution, and other reactions to introduce the 4-bromo-3-fluorobenzoyl moiety.

Basic Information

Product Name	4-Bromo-3-Fluorobenzoyl Chloride
CAS No.	695188-21-7
Molecular Formula	C7H3BrClFO
Molecular Weight	237.45 g/mol
Synonyms	4-Bromo-3-fluorobenzoic acid chloride; 3-Fluoro-4-bromobenzoyl chloride; Benzoic acid, 4-bromo-3-fluoro-, chloride; 4-Bromo-3-fluorobenzoyl chloride; 4-Bromo-3-fluoro-benzoic acid chloride; 4-Bromo-3-fluorobenzoic acid chloride; 695188-21-7
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Fluorobenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines. Due to its acid chloride nature and sensitivity to moisture, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.