Description

2-Bromo-4-Trifluoromethylphenylisothiocyanate is a specialized aromatic isothiocyanate derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromo and trifluoromethyl substituents, makes it a versatile reagent for introducing functional complexity into target molecules. This compound is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the isothiocyanate and trifluoromethyl groups.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functional polymers and advanced organic materials with specific electronic or surface properties.
• Chemical Biology Probe: Useful for modifying proteins or other biomolecules due to the reactive isothiocyanate group, aiding in bioconjugation and labeling studies.
• Custom Synthesis and Contract Manufacturing: A high-value intermediate for custom synthesis houses serving the fine chemical and life science sectors.

Basic Information

Product Name	2-Bromo-4-Trifluoromethylphenylisothiocyanate
CAS No.	688763-22-6
Molecular Formula	C8H3BrF3NS
Molecular Weight	282.08 g/mol
Synonyms	2-Bromo-α,α,α-trifluoro-p-tolyl isothiocyanate; 1-Bromo-2-isothiocyanato-5-(trifluoromethyl)benzene; 2-Bromo-4-(trifluoromethyl)phenyl isothiocyanate; Isothiocyanic acid, 2-bromo-4-(trifluoromethyl)phenyl ester; 2-Bromo-α,α,α-trifluoro-p-tolyl mustard oil
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Trifluoromethylphenylisothiocyanate is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee it meets your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.