Description

3-Fluorophenylsulfonylethanol is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a sulfonyl and a fluorophenyl group attached to an ethanol linker, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the fluorine atom and sulfonyl group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification Agent: Employed to introduce fluorinated sulfonyl functionalities into polymer backbones, altering properties like chemical resistance, surface energy, and thermal stability.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create more complex biaryl structures for various applications.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	3-Fluorophenylsulfonylethanol
CAS No.	685892-13-1
Molecular Formula	C8H9FO3S
Molecular Weight	204.22 g/mol
Synonyms	2-[(3-Fluorophenyl)sulfonyl]ethanol; 1-(3-Fluorophenyl)sulfonyl-2-ethanol; 3-Fluorobenzenesulfonylethanol; 2-Hydroxyethyl 3-fluorophenyl sulfone; β-Hydroxyethyl 3-fluorophenyl sulfone; (3-Fluorophenyl)(2-hydroxyethyl)sulfone; 3-Fluoro-ω-hydroxyethyl phenyl sulfone
EINECS	Contact for details

Quality Control

Our 3-Fluorophenylsulfonylethanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.