Description

(-)-Camphanyldimethylchlorosilane is a high-purity, chiral organosilicon reagent featuring a camphor-derived scaffold. This compound matters as a versatile chiral auxiliary and derivatization agent, enabling the synthesis of enantiomerically pure compounds critical for advanced research and development. It is needed by pharmaceutical, agrochemical, and specialty chemical manufacturers for applications in asymmetric synthesis, chiral chromatography, and the production of high-value intermediates.

Application

• Chiral Derivatization Agent: Used for the resolution of enantiomers in analytical chemistry, particularly in HPLC and GC for chiral separation and analysis.
• Asymmetric Synthesis: Serves as a chiral auxiliary or ligand precursor in stereoselective catalytic reactions and organometallic chemistry.
• Pharmaceutical Intermediates: A key building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and complex natural products.
• Surface Modification: Employed to introduce chiral centers onto silica surfaces or other materials for creating chiral stationary phases.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Advanced Material Science: A precursor for synthesizing chiral silanes and siloxanes used in specialty polymers and functional materials.

Basic Information

Product Name	(-)-Camphanyldimethylchlorosilane
CAS No.	684284-12-6
Molecular Formula	C₁₂H₂₁ClSi
Molecular Weight	228.84 g/mol
Synonyms	(-)-10-Camphorsulfonyldimethylchlorosilane; (1S,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-yl)dimethylchlorosilane; Camphor-10-sulfonyl dimethylchlorosilane; Chiral camphor chlorosilane; Dimethyl[(1S,4R)-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl]chlorosilane; (1S)-(-)-Camphanyldimethylchlorosilane
EINECS	Contact for details

Quality Control

Our (-)-Camphanyldimethylchlorosilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC and NMR spectroscopy, to ensure compliance with exacting standards for research and industrial use. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.