Description

4-Pyrimidin-2-Ylbenzoyl Chloride is a high-purity organic intermediate characterized by its reactive benzoyl chloride functional group linked to a pyrimidine heterocycle. This compound is critical for introducing the 4-pyrimidin-2-ylbenzoyl moiety into target molecules, enabling the synthesis of complex structures with precision. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of small molecule drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Serves as a precursor for functional polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: An essential reagent for peptide coupling and amide bond formation reactions in complex organic synthesis.
• Bioconjugation: Facilitates the labeling and modification of biomolecules for diagnostic and research applications.

Basic Information

Item	Details
Product Name	4-Pyrimidin-2-Ylbenzoyl Chloride
CAS No.	679806-84-9
Molecular Formula	C11H7ClN2O
Molecular Weight	218.64 g/mol
Synonyms	4-(Pyrimidin-2-yl)benzoyl chloride; 2-(4-Chlorocarbonylphenyl)pyrimidine; 4-Pyrimidin-2-yl-benzoic acid chloride; p-(2-Pyrimidyl)benzoyl chloride; (4-Pyrimidin-2-ylphenyl)methanoyl chloride
EINECS	Contact for details

Quality Control

Our 4-Pyrimidin-2-Ylbenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.