Description

(E)-3-(4-Bromo-2-Fluorophenyl)Acryloyl Chloride is a high-purity, reactive chemical intermediate designed for advanced synthesis. This compound is valued for its role as a key building block in the creation of complex, biologically active molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel small-molecule drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the creation of complex ligands for metal-organic frameworks (MOFs) and catalytic systems.
• Chemical Biology Probes: Utilized to synthesize fluorescent or affinity tags for studying biological pathways and protein interactions.

Basic Information

Product Name	(E)-3-(4-Bromo-2-Fluorophenyl)Acryloyl Chloride
CAS No.	676348-49-5
Molecular Formula	C9H5BrClFO
Molecular Weight	263.49 g/mol
Synonyms	(E)-3-(4-Bromo-2-fluorophenyl)prop-2-enoyl chloride; 4-Bromo-2-fluorocinnamoyl chloride; (2E)-3-(4-Bromo-2-fluorophenyl)-2-propenoyl chloride; trans-3-(4-Bromo-2-fluorophenyl)acryloyl chloride; 676348-49-5; (E)-4-Bromo-2-fluorocinnamoyl chloride; 2-Propenoyl chloride, 3-(4-bromo-2-fluorophenyl)-, (2E)-
EINECS	Contact for details

Quality Control

Our (E)-3-(4-Bromo-2-Fluorophenyl)Acryloyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We can support development and commercial projects with material produced under cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and highly volatile; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture uptake. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.