Description

1-p-Tolyl-Cyclohexanecarbonyl Chloride is a specialized organic intermediate featuring a reactive acid chloride functional group. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel compounds and active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the cyclohexane and aryl motifs are common structural components.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and advanced organic materials with specific optical or electronic properties.
• Chemical Biology & Proteomics: Employed as a reagent for modifying proteins, peptides, or other biomolecules to study biological pathways or create diagnostic tools.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory synthesis in organic chemistry.
• Custom Synthesis & Scale-up: A starting point for contract manufacturing organizations (CMOs) to produce custom-designed compounds for client projects at various scales.

Basic Information

Product Name	1-p-Tolyl-Cyclohexanecarbonyl Chloride
CAS No.	676348-46-2
Molecular Formula	C14H17ClO
Molecular Weight	236.74 g/mol
Synonyms	1-(4-Methylphenyl)cyclohexanecarbonyl chloride; 1-(p-Tolyl)cyclohexanecarbonyl chloride; 4-Methyl-α-(1-chlorocarbonylcyclohexyl)benzene; Cyclohexanecarbonyl chloride, 1-(4-methylphenyl)-; p-Tolylcyclohexanecarbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 1-p-Tolyl-Cyclohexanecarbonyl Chloride is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of heat.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.