Description

3-(Cyclopropylmethoxy)-4-(Difluoromethoxy)Benzoyl Chloride is a high-purity, reactive benzoyl chloride derivative designed for advanced synthetic chemistry. This compound serves as a critical building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique difluoromethoxy and cyclopropylmethoxy substituents introduce specific steric and electronic properties. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures. The product is supplied with a guaranteed Certificate of Analysis to ensure batch-to-batch consistency and reliability for your sensitive processes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, where the difluoromethoxy group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers and liquid crystals, where its aromatic core and functional groups modify material properties.
• Custom Synthesis and Contract Manufacturing: An essential reagent for CDMOs (Contract Development and Manufacturing Organizations) and fine chemical suppliers producing bespoke compounds for client projects.

Basic Information

Product Name	3-(Cyclopropylmethoxy)-4-(Difluoromethoxy)Benzoyl Chloride
CAS No.	672883-68-0
Molecular Formula	C12H11ClF2O3
Molecular Weight	276.66 g/mol
Synonyms	4-(Difluoromethoxy)-3-(cyclopropylmethoxy)benzoyl chloride; 3-Cyclopropylmethoxy-4-difluoromethoxybenzoyl chloride; Benzoyl chloride, 3-(cyclopropylmethoxy)-4-(difluoromethoxy)-; 672883-68-0; 3-CPM-4-DFMB-Cl
EINECS	Contact for details

Quality Control

Every batch of 3-(Cyclopropylmethoxy)-4-(Difluoromethoxy)Benzoyl Chloride is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its reactivity as an acid chloride and sensitivity to moisture, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.