Description

1,3,5,7-Cyclooctatetraene-1-Carbonyl Chloride (9Ci) is a highly reactive and versatile chemical intermediate, specifically an acyl chloride derivative of cyclooctatetraene. This compound matters for its unique structure, which combines the non-aromatic, tub-shaped cyclooctatetraene ring with a reactive carbonyl chloride group, enabling its use in advanced synthetic chemistry. It is primarily needed by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing complex molecular architectures, including potential ligands and novel organic frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and coordination chemistry, leveraging the unique electronic properties of the cyclooctatetraene backbone.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials with tailored properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for Friedel-Crafts acylation, amide bond formation, and other reactions where a reactive acylating agent is required.
• Chemical Research: Utilized in fundamental studies of strained-ring systems and pericyclic reactions due to its distinctive non-aromatic, conjugated structure.

Basic Information

Product Name	1,3,5,7-Cyclooctatetraene-1-Carbonyl Chloride (9Ci)
CAS No.	663618-22-2
Molecular Formula	C9H7ClO
Molecular Weight	166.60 g/mol
Synonyms	Cyclooctatetraenecarbonyl chloride; 1,3,5,7-Cyclooctatetraene-1-carbonyl chloride; COT-carbonyl chloride; (Cycloocta-1,3,5,7-tetraen-1-yl)carbonyl chloride; 1-Chlorocarbonyl-1,3,5,7-cyclooctatetraene; Cyclooctatetraene-1-carbonyl chloride; 1-Carboxycyclooctatetraene chloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, it should be kept under an inert atmosphere (e.g., nitrogen or argon) and separated from bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.