Description

3-Fluoro-2-Hydroxymethyl-Phenol is a versatile fluorinated phenolic compound with a reactive hydroxymethyl group. This unique structure makes it a valuable building block for synthesizing more complex molecules in advanced chemical research and manufacturing. It is primarily used by pharmaceutical intermediates and agrochemical developers, as well as in the creation of specialty polymers and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic scaffold.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed coupling reactions and asymmetric synthesis.
• Polymer Modification: Incorporated into polymer backbones to impart specific properties like altered solubility, thermal stability, or reactivity.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fluorinated compounds for material science and electronic chemicals.
• Research & Development: A valuable reagent for medicinal chemistry and chemical biology research exploring new fluorinated molecular entities.

Basic Information

Product Name	3-Fluoro-2-Hydroxymethyl-Phenol
CAS No.	660390-77-2
Molecular Formula	C7H7FO2
Molecular Weight	142.13 g/mol
Synonyms	2-(Hydroxymethyl)-3-fluorophenol; 3-Fluoro-2-(hydroxymethyl)phenol; 3-Fluoro-2-hydroxybenzyl alcohol; 2-Hydroxymethyl-3-fluorophenol; Phenol, 3-fluoro-2-(hydroxymethyl)-; 3-Fluoro salicyl alcohol; 3-Fluoro-2-hydroxybenzyl alcohol; 660390-77-2
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Hydroxymethyl-Phenol is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.