Description

1-Methyl-4-Phenyl-1H-Imidazole-5-Carbonyl Chloride is a high-value, reactive chemical intermediate primarily used in advanced organic synthesis. Its core value lies in its role as a versatile building block for constructing complex heterocyclic frameworks, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those containing imidazole or related heterocyclic cores.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides where the imidazole moiety imparts specific biological activity.
• Material Science: Serves as a precursor for functional polymers, ligands for catalysis, and advanced organic materials.
• Academic & R&D: A critical reagent in university and corporate research laboratories for exploring new chemical reactions and synthesizing complex molecules.
• Peptide Mimetics: Employed in the design and synthesis of peptidomimetics and other bio-active compounds.

Basic Information

Product Name	1-Methyl-4-Phenyl-1H-Imidazole-5-Carbonyl Chloride
CAS No.	655253-59-1
Molecular Formula	C11H9ClN2O
Molecular Weight	220.66 g/mol
Synonyms	1-Methyl-4-phenyl-1H-imidazole-5-carbonyl chloride; 1-Methyl-4-phenylimidazole-5-carbonyl chloride; 5-(Chlorocarbonyl)-1-methyl-4-phenyl-1H-imidazole; 1-Methyl-4-phenyl-1H-imidazole-5-carboxylic acid chloride; 1-Methyl-4-phenylimidazole-5-carboxylic acid chloride; 4-Phenyl-1-methyl-1H-imidazole-5-carbonyl chloride; 1-Methyl-4-phenyl-1H-imidazole-5-carboxyl chloride
EINECS	Contact for details

Quality Control

Our 1-Methyl-4-Phenyl-1H-Imidazole-5-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from incompatible materials such as strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.