Description

4-(Morpholine-4-Sulfonyl)-Benzoyl Chloride is a high-purity, reactive chemical intermediate featuring a benzoyl chloride core functionalized with a morpholine sulfonyl group. This compound matters for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate this specific sulfonamide-linked aromatic acid chloride moiety into target compounds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting enzymes where the morpholine sulfonyl benzamide structure is pharmacologically relevant.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require sulfonamide-based scaffolds.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers and functional materials with specific surface properties.
• Chemical Biology & Proteomics: Employed as a reagent for modifying proteins or synthesizing activity-based probes to study enzyme function and inhibition.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	4-(Morpholine-4-Sulfonyl)-Benzoyl Chloride
CAS No.	654682-86-7
Molecular Formula	C11H12ClNO4S
Molecular Weight	289.73 g/mol
Synonyms	4-(Morpholine-4-sulfonyl)benzoyl chloride; 4-(4-Morpholinosulfonyl)benzoyl chloride; 4-Morpholinosulfonylbenzoyl chloride; Benzoic acid, 4-(4-morpholinylsulfonyl)-, chloride; p-(Morpholinosulfonyl)benzoyl chloride; 4-(N-Morpholinosulfonyl)benzoyl chloride
EINECS	Contact for details

Quality Control

Our 4-(Morpholine-4-Sulfonyl)-Benzoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.