Description

2-Bromopyridine-3-Carbonyl Chloride is a versatile and highly reactive organic building block, essential for constructing complex molecular architectures. Its core value lies in its dual functionality as both an electrophilic acid chloride and a halogenated heterocycle, enabling efficient synthesis of amides, esters, and further functionalized pyridine derivatives. This compound is critically needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require bromopyridine motifs for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functional organic molecules for electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Peptide Mimetics & Bioconjugation: Facilitates the introduction of pyridine-based groups into peptides or proteins for bioconjugation and probe development.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse R&D projects.

Basic Information

Item	Details
Product Name	2-Bromopyridine-3-Carbonyl Chloride
CAS No.	654084-12-5
Molecular Formula	C6H3BrClNO
Molecular Weight	220.45 g/mol
Synonyms	3-(Chlorocarbonyl)-2-bromopyridine; 2-Bromo-3-pyridinecarbonyl chloride; 2-Bromonicotinoyl chloride; 2-Bromopyridine-3-carboxylic acid chloride; 2-Bromo-3-pyridinylcarbonyl chloride; 2-Bromonicotinic acid chloride; 2-Bromo-3-carboxypyridine chloride; 654084-12-5
EINECS	Contact for details

Quality Control

Every batch of 2-Bromopyridine-3-Carbonyl Chloride is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by techniques such as HPLC, NMR, and GC is supplied with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, the container should be kept under an inert atmosphere (e.g., nitrogen or argon) after opening. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.