Description

Brivanib Alaninate is a small molecule inhibitor targeting vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) tyrosine kinases. This compound is of significant interest in pharmaceutical research and development for its potential therapeutic applications. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology drug discovery and preclinical studies.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in the development of novel anti-cancer therapies.
• Preclinical Studies: Used in in vitro and in vivo models to investigate mechanisms of angiogenesis inhibition and tumor growth suppression.
• Biochemical Assays: Employed as a potent and selective inhibitor in kinase profiling and signal transduction pathway analysis.
• Formulation Development: Acts as the core component in the development of various dosage forms for clinical trial materials (CTM).

Basic Information

Product Name	Brivanib Alaninate
CAS No.	649735-63-7
Molecular Formula	C22H21FN4O5
Molecular Weight	440.43 g/mol
Synonyms	BMS-582664; (R)-1-(4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan-2-yl 2-aminopropanoate; Brivanib alaninate; UNII-6E3K6W3LPC; BMS582664
EINECS	Contact for details

Quality Control

Our Brivanib Alaninate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research materials. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting results for assay, related substances, residual solvents, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.