Description

3-Bromo-6-Fluoro-2-Methoxybenzenemethanol is a high-purity, multi-functional aromatic building block of significant interest in advanced organic synthesis. Its unique substitution pattern, featuring bromo, fluoro, and methoxy groups adjacent to a benzylic alcohol, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Serves as a crucial building block for creating novel herbicides, fungicides, and insecticides, leveraging the bioactivity-modifying properties of its halogen and ether substituents.
• Material Science Research: Used in the synthesis of specialized monomers for advanced polymers, liquid crystals, or organic electronic materials due to its rigid, substituted benzene core.
• Chemical Biology & Proteomics: Can be employed as a linker or tagging reagent in the development of chemical probes for studying biological systems and protein function.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Bromo-6-Fluoro-2-Methoxybenzenemethanol
CAS No.	648439-20-7
Molecular Formula	C8H8BrFO2
Molecular Weight	235.05 g/mol
Synonyms	(3-Bromo-6-fluoro-2-methoxyphenyl)methanol; 2-(Hydroxymethyl)-3-bromo-6-fluoroanisole; 1-(3-Bromo-6-fluoro-2-methoxyphenyl)methanol; Benzenemethanol, 3-bromo-6-fluoro-2-methoxy-; 3-Bromo-6-fluoro-2-methoxybenzyl alcohol
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Fluoro-2-Methoxybenzenemethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.