Description

4-Ethoxy-3-(Trifluoromethyl)Benzoyl Chloride, 97% is a high-purity, reactive organic intermediate belonging to the class of substituted benzoyl chlorides. This compound is a critical building block in advanced organic synthesis, valued for its ability to introduce the 4-ethoxy-3-(trifluoromethyl)benzoyl moiety into target molecules. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethyl-substituted aromatic system for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the ethoxy and trifluoromethyl groups contribute to biological activity and selectivity.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Polymer Chemistry: Acts as a monomer or modifying agent for introducing specific functional groups into polymer chains to alter material properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for Friedel-Crafts acylation, amide coupling, and esterification reactions to create complex molecular architectures.
• Dye and Pigment Intermediate: Used in the synthesis of specialized dyes and pigments, leveraging the electron-withdrawing trifluoromethyl group to tune color properties.

Basic Information

Item	Details
Product Name	4-Ethoxy-3-(Trifluoromethyl)Benzoyl Chloride, 97%
CAS No.	647010-69-3
Molecular Formula	C10H8ClF3O2
Molecular Weight	252.62 g/mol
Synonyms	4-Ethoxy-3-(trifluoromethyl)benzoyl chloride; 3-Trifluoromethyl-4-ethoxybenzoyl chloride; 4-Ethoxy-alpha,alpha,α-trifluoro-m-toluoyl chloride; 647010-69-3; Benzoyl chloride, 4-ethoxy-3-(trifluoromethyl)-; m-Toluoyl chloride, alpha,alpha,α-trifluoro-4-ethoxy-
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-3-(Trifluoromethyl)Benzoyl Chloride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure it meets the specified 97% minimum purity and consistent impurity profile. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and assay results is provided with every shipment to guarantee traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizers, and sources of moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.