Description

6-Methyl-3-(β-D-2-Ribofuranosyl)Pyrrolo[2,3-D]Pyrimidin-2-One is a sophisticated nucleoside analog building block of significant interest in advanced pharmaceutical research and development. Its core value lies in its role as a key synthetic intermediate for novel antiviral and anticancer therapeutics, enabling the creation of targeted, high-potency drug candidates. This compound is essential for R&D chemists and process development scientists working in pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, well-characterized intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside-based antiviral agents targeting specific viral polymerases.
• Anticancer Drug Development: Used in research programs focused on creating small molecule inhibitors that interfere with cancer cell proliferation pathways.
• Biochemical Research: Serves as a specialized substrate or inhibitor in enzymatic studies and mechanism of action (MOA) investigations.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Custom Synthesis & Contract Manufacturing: A key building block for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client pipelines.

Basic Information

Product Name	6-Methyl-3-(β-D-2-Ribofuranosyl)Pyrrolo[2,3-D]Pyrimidin-2-One
CAS No.	644962-84-5
Molecular Formula	C₁₂H₁₅N₃O₅
Molecular Weight	281.26 g/mol
Synonyms	6-Methyl-3-β-D-ribofuranosylpyrrolo[2,3-d]pyrimidin-2(3H)-one; 3-β-D-Ribofuranosyl-6-methylpyrrolo[2,3-d]pyrimidin-2-one; 6-Methyl-3-(β-D-ribofuranosyl)-2,3-dihydro-7H-pyrrolo[2,3-d]pyrimidin-2-one; Nucleoside analog intermediate; Pyrrolopyrimidine riboside; 644962-84-5
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity suitable for research and development applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.