Description

2-(3-Trifluoromethoxyphenyl)Ethanol is a versatile fluorinated aromatic alcohol building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of the trifluoromethoxy group, which enhances lipophilicity and metabolic stability, and the reactive ethanol side chain, enabling further functionalization. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients, as well as in material science for creating specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for constructing bioactive molecules, particularly in the development of CNS (Central Nervous System) agents, anti-inflammatory drugs, and antiviral compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group contributes to improved efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens, which are critical components in high-performance display technologies.
• Polymer Modification: Incorporated as a monomer or chain modifier to impart specific properties like chemical resistance, thermal stability, and altered surface characteristics to specialty polymers.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, esterifications, and etherifications to introduce the 3-(trifluoromethoxy)phenyl moiety into more complex molecular architectures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating libraries of novel fluorinated compounds for screening.

Basic Information

Product Name	2-(3-Trifluoromethoxyphenyl)Ethanol
CAS No.	642444-30-2
Molecular Formula	C9H9F3O2
Molecular Weight	206.16 g/mol
Synonyms	3-(Trifluoromethoxy)phenethyl alcohol; 2-[3-(Trifluoromethoxy)phenyl]ethan-1-ol; 1-(3-Trifluoromethoxyphenyl)-2-ethanol; m-Trifluoromethoxyphenethyl alcohol; 2-(3-(Trifluoromethoxy)phenyl)ethanol; α-(3-Trifluoromethoxyphenyl)ethanol (incorrect but common); 3-Trifluoromethoxyphenylethanol
EINECS	Contact for details

Quality Control

Our 2-(3-Trifluoromethoxyphenyl)Ethanol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including GC, HPLC, NMR, and IR spectroscopy for comprehensive identity confirmation and impurity profiling. Certificates of Analysis (COA) detailing all relevant specifications are provided with each shipment and are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which could affect product quality and stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.