Description

Iptakalim Hydrochloride is a high-purity, small-molecule pharmaceutical intermediate and research chemical. This compound is of significant interest in the development of novel therapeutic agents, particularly in the cardiovascular and neurological research fields. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) for preclinical and process development studies.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of new drug candidates, particularly those targeting ion channels.
• Preclinical Studies: Used in pharmacological and toxicological evaluations to investigate mechanism of action, efficacy, and safety profiles.
• Process Chemistry & Scale-Up: Employed in the development and optimization of synthetic routes for the production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for biochemical and physiological studies related to its pharmacological class.
• Analytical Reference Standard: Acts as a high-purity compound for method development, validation, and quality control testing in analytical laboratories.
• Chemical Library Synthesis: Used as a building block for creating diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	Iptakalim Hydrochloride
CAS No.	642407-63-4
Molecular Formula	C9H15ClN2O • HCl
Molecular Weight	247.15 g/mol
Synonyms	Iptakalim HCl; N-(1,3-Dimethyl-4-propyl-1H-pyrazol-5-yl)-N'-cyano-guanidine monohydrochloride; 1-[(1,3-Dimethyl-4-propylpyrazol-5-yl)carbamimidoyl]guanidine hydrochloride; BMS-303213; Iptakalim (hydrochloride)
EINECS	Contact for details

Quality Control

Our Iptakalim Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with a detailed Certificate of Analysis (COA) that includes results from HPLC, NMR, and MS analyses. Our quality commitment aligns with the standards expected for pharmaceutical research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.