Description

5-Methyl-1-(β-L-Ribofuranosyl)Uracil is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a key building block and intermediate in the synthesis of novel antiviral and anticancer agents, particularly those targeting RNA-based mechanisms. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of nucleoside-based therapeutics and diagnostic probes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and RNA processing.
• Antiviral Drug Development: Serves as a core scaffold for researching compounds active against RNA viruses.
• Pro-drug Synthesis: Employed in the design and synthesis of pro-drugs to enhance bioavailability and targeting of therapeutic nucleosides.
• Diagnostic Probe Development: Utilized in creating labeled nucleotides for molecular diagnostics and imaging.
• Academic Research: A valuable tool for studying the structure-activity relationships (SAR) of modified nucleosides.

Basic Information

Product Name	5-Methyl-1-(β-L-Ribofuranosyl)Uracil
CAS No.	642082-80-2
Molecular Formula	C10H14N2O6
Molecular Weight	258.23 g/mol
Synonyms	5-Methyluridine, L-Isomer; 5-Methyl-1-β-L-ribofuranosyluracil; β-L-5-Methyluridine; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-5-methylpyrimidine-2,4-dione; L-5-Methyluridine; 5-Methyl-L-uridine; 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-β-L-ribofuranosyl-
EINECS	Contact for details

Quality Control

Our 5-Methyl-1-(β-L-Ribofuranosyl)Uracil is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent moisture uptake and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.