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4-(Azidomethyl)-2-Thiazolamine CAS NO 640767-57-3
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CAS No.:640767-57-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4-(Azidomethyl)-2-Thiazolamine is a specialized heterocyclic building block containing both an azide and an amine functional group. This unique bifunctional structure makes it a valuable intermediate for click chemistry and bioconjugation applications in advanced research and development. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers for synthesizing novel compounds, including potential drug candidates and molecular probes.
Application
- Pharmaceutical Intermediate: A key precursor in the synthesis of novel thiazole-based active pharmaceutical ingredients (APIs) and drug candidates.
- Click Chemistry Reagent: The azide group enables efficient, high-yielding Huisgen 1,3-dipolar cycloaddition reactions with alkynes for bioconjugation and polymer chemistry.
- Agrochemical Research: Used in developing new fungicides, herbicides, or insecticides that incorporate the thiazole moiety.
- Material Science: Serves as a building block for creating functional polymers, dendrimers, or surface coatings with specific chemical properties.
- Bioconjugation & Probe Synthesis: Facilitates the labeling of biomolecules (proteins, antibodies) or the creation of fluorescent or affinity probes for diagnostic and research purposes.
- Chemical Biology: Employed in activity-based protein profiling (ABPP) and the development of enzyme inhibitors or modulators.
Basic Information
| Item | Details |
|---|---|
| Product Name | 4-(Azidomethyl)-2-Thiazolamine |
| CAS No. | 640767-57-3 |
| Molecular Formula | C4H5N5S |
| Molecular Weight | 155.18 g/mol |
| Synonyms | 2-Amino-4-(azidomethyl)thiazole; 4-(Azidomethyl)thiazol-2-amine; 2-Thiazolamine, 4-(azidomethyl)-; 4-Azidomethyl-2-aminothiazole; 4-(Azidomethyl)-2-aminothiazole; 4-(Azidomethyl)-1,3-thiazol-2-amine |
| EINECS | Contact for details |
Quality Control
Our 4-(Azidomethyl)-2-Thiazolamine is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or crystalline solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% (Typical: 97-99%) |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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