Description

2-Pyridinecarbonyl Chloride, 4-Ethyl- (9Ci) is a versatile and reactive heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the 4-ethylpyridine-2-carbonyl moiety, enabling the construction of complex molecules with tailored properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyridine core contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Functional Material Development: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers requiring specific pyridine-based functionalities.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and compound libraries.
• Peptide Mimetic and Bio-conjugation: Facilitates the introduction of lipophilic, aromatic groups into peptides or proteins for bio-conjugation and probe development.

Basic Information

Item	Detail
Product Name	2-Pyridinecarbonyl Chloride, 4-Ethyl- (9Ci)
CAS No.	640296-11-3
Molecular Formula	C8H8ClNO
Molecular Weight	169.61 g/mol
Synonyms	4-Ethylpicolinoyl chloride; 4-Ethylpyridine-2-carbonyl chloride; 2-Pyridinecarbonyl chloride, 4-ethyl-; 4-Ethyl-2-pyridinecarboxylic acid chloride; 4-Ethylpicolinic acid chloride; Picolinoyl chloride, 4-ethyl-; 4-Ethyl-2-picolinoyl chloride
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarbonyl Chloride, 4-Ethyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.