Description

2-Pyridinecarbonyl Chloride, 4-Methyl- (9Ci) is a versatile and highly reactive acid chloride derivative of picolinic acid, serving as a critical building block in advanced organic synthesis. Its core value lies in its ability to efficiently introduce the 4-methylpyridine-2-carbonyl moiety, enabling the construction of complex molecules with precision. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyridine core provides specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Monomer: Employed in the synthesis of functional polymers and organic electronic materials that require conjugated heterocyclic structures.
• Chemical Biology Probe Synthesis: Facilitates the labeling and modification of biomolecules for diagnostic and research applications.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for fine chemical and custom synthesis houses serving diverse R&D and scale-up projects.

Basic Information

Product Name	2-Pyridinecarbonyl Chloride, 4-Methyl- (9Ci)
CAS No.	640296-10-2
Molecular Formula	C7H6ClNO
Molecular Weight	155.58 g/mol
Synonyms	4-Methylpicolinoyl chloride; 4-Methylpyridine-2-carbonyl chloride; 2-Pyridinecarbonyl chloride, 4-methyl-; 4-Methyl-2-picolinoyl chloride; 4-Methylpicolinic acid chloride; 4-Methyl-2-pyridinecarboxylic acid chloride; 4-Methylpyridine-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarbonyl Chloride, 4-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.