Description

3-Pyridinecarbonylchloride,2-(Cyclopropylamino)-(9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the introduction of both cyclopropylamino and reactive carbonyl chloride functionalities. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the pyridine and cyclopropyl moieties are common pharmacophores.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or binding properties.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Pyridinecarbonylchloride,2-(Cyclopropylamino)-(9Ci)
CAS No.	639807-23-1
Molecular Formula	C9H9ClN2O
Molecular Weight	196.63 g/mol
Synonyms	2-(Cyclopropylamino)nicotinoyl chloride; 2-(Cyclopropylamino)pyridine-3-carbonyl chloride; 3-Pyridinecarbonyl chloride, 2-(cyclopropylamino)-; 2-Cyclopropylaminonicotinoyl chloride; Nicotinoyl chloride, 2-(cyclopropylamino)-; 2-(Cyclopropylamino)-3-pyridinecarbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarbonylchloride,2-(Cyclopropylamino)-(9Ci) is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, is performed to verify identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and away from moisture, strong bases, and oxidizing agents. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.