Description

Di-Tert.-Butyl 4-Azido-2,6-Pyridinedicarboxylate is a specialized pyridine derivative functionalized with azido and tert-butyl ester groups, serving as a versatile synthetic intermediate. Its value lies in its role as a key precursor for click chemistry applications, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs utilizing Huisgen 1,3-dipolar cycloaddition (click chemistry).
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its reactive azide group allows for the modular attachment of bioactive moieties.
• Polymer & Material Science: Serves as a functional monomer or cross-linking agent for creating advanced polymers with tailored properties, such as hydrogels or smart materials.
• Bioconjugation: Facilitates the labeling and modification of biomolecules (proteins, peptides, oligonucleotides) for diagnostic and therapeutic applications.
• Ligand Synthesis for Catalysis: Employed in the preparation of complex ligands used in homogeneous catalysis and coordination chemistry.
• Chemical Probe Development: Utilized in academic and industrial R&D to create probes for studying biological pathways and mechanisms.

Basic Information

Product Name	Di-Tert.-Butyl 4-Azido-2,6-Pyridinedicarboxylate
CAS No.	638128-20-8
Molecular Formula	C16H20N4O4
Molecular Weight	332.36 g/mol
Synonyms	4-Azido-2,6-pyridinedicarboxylic acid di-tert-butyl ester; Di-tert-butyl 4-azidopyridine-2,6-dicarboxylate; 2,6-Pyridinedicarboxylic acid, 4-azido-, 1,6-di-tert-butyl ester; 4-Azido-2,6-bis(tert-butoxycarbonyl)pyridine; DTBPADC; tert-Butyl 4-azido-2,6-pyridinedicarboxylate
EINECS	Contact for details

Quality Control

Our Di-Tert.-Butyl 4-Azido-2,6-Pyridinedicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.