Description

4-{[3-(Trifluoromethyl)Benzyl]Oxy}Benzoyl Chloride is a high-purity, specialized benzoyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a trifluoromethyl-substituted benzyloxy group, makes it a valuable reagent for introducing specific aromatic motifs into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethyl group.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating specialized aromatic cores in electronic display and lighting materials.
• Polymer Modification: Employed to introduce benzoyl and fluorinated aromatic groups into polymer chains, enhancing material properties like thermal stability and chemical resistance.
• Organic Synthesis Reagent: A versatile acylating agent for the preparation of esters, amides, and ketones in complex multi-step synthetic routes.
• Research & Development: Critical tool in medicinal chemistry and material science R&D for exploring new chemical entities and structure-activity relationships.

Basic Information

Product Name	4-{[3-(Trifluoromethyl)Benzyl]Oxy}Benzoyl Chloride
CAS No.	632366-17-7
Molecular Formula	C15H10ClF3O2
Molecular Weight	314.69 g/mol
Synonyms	4-[(3-(Trifluoromethyl)benzyl)oxy]benzoyl chloride; 4-((3-(Trifluoromethyl)benzyl)oxy)benzoyl chloride; 4-(3-Trifluoromethylbenzyloxy)benzoyl Chloride; 4-[(α,α,α-Trifluoro-m-tolyl)methoxy]benzoyl chloride; Benzoyl chloride, 4-[[[3-(trifluoromethyl)phenyl]methyl]oxy]-; 632366-17-7; 4-(3-Trifluoromethyl-benzyloxy)-benzoyl chloride
EINECS	Contact for details

Quality Control

Our 4-{[3-(Trifluoromethyl)Benzyl]Oxy}Benzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis. Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider refrigeration (2-8°C) under desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.