Description

5'-o-(2-Amino-2-Deoxy-D-Glucopyranosyl)-Cytidine is a sophisticated nucleoside derivative where a 2-amino-2-deoxy-D-glucopyranose moiety is linked to the 5'-position of cytidine. This compound matters as a key building block and reference standard in advanced pharmaceutical research and development, particularly for the synthesis of novel nucleoside analogs and prodrugs. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries working on antiviral agents, anticancer therapeutics, and other nucleoside-based drug candidates.

Application

• Pharmaceutical Intermediate: Critical starting material or advanced intermediate in the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate glycosyltransferase activity and carbohydrate-nucleic acid interactions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Prodrug Development: Utilized in research focused on designing prodrugs to enhance the bioavailability and targeting of nucleoside therapeutics.
• Glycoconjugate Synthesis: Acts as a key precursor in the chemical and enzymatic synthesis of complex glycoconjugates for biological evaluation.
• Antisense Oligonucleotide Research: Potential use in the development of modified oligonucleotides with altered pharmacokinetic properties.

Basic Information

Product Name	5'-o-(2-Amino-2-Deoxy-D-Glucopyranosyl)-Cytidine
CAS No.	631842-23-4
Molecular Formula	C15H22N4O9
Molecular Weight	402.36 g/mol
Synonyms	5'-O-(2-Amino-2-deoxy-β-D-glucopyranosyl)cytidine; Cytidine, 5'-O-(2-amino-2-deoxy-D-glucopyranosyl)-; 2-Amino-2-deoxy-D-glucopyranosyl cytidine; N4-[(2-Amino-2-deoxy-D-glucopyranosyl)oxy]cytidine (tautomeric form); 5'-Glucosylcytidine derivative; Amino sugar-conjugated cytidine; Cytidine 5'-glucosamine conjugate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to cGMP principles for the manufacture of pharmaceutical intermediates to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.