Description

5'-o-(2-Amino-2-Deoxy-β-D-Glucopyranosyl)-Uridine is a sophisticated nucleoside derivative where a glucosamine moiety is linked to the 5'-position of uridine. This compound is of significant interest in advanced biochemical research and pharmaceutical development due to its unique structure, which combines the properties of a nucleoside with an amino sugar. It serves as a critical intermediate or reference standard for researchers in medicinal chemistry, particularly in the development of novel antiviral agents, carbohydrate-based therapeutics, and as a tool for studying glycosylation processes and enzyme mechanisms.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel nucleoside analog prodrugs and antiviral compounds.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for glycosyltransferases and nucleoside-metabolizing enzymes.
• Medicinal Chemistry: Serves as a reference standard and a starting material for structure-activity relationship (SAR) studies in drug discovery programs.
• Glycobiology Studies: A valuable tool for investigating carbohydrate-nucleoside interactions, cell signaling pathways, and the role of glycosylation in biological systems.
• Diagnostic Reagent Development: Potential use in the development of diagnostic assays and probes for detecting specific enzymatic activities.

Basic Information

Product Name	5'-o-(2-Amino-2-Deoxy-β-D-Glucopyranosyl)-Uridine
CAS No.	631842-22-3
Molecular Formula	C15H23N3O11
Molecular Weight	421.36 g/mol
Synonyms	5'-O-(2-Amino-2-deoxy-β-D-glucopyranosyl)uridine; Uridine, 5'-O-(2-amino-2-deoxy-β-D-glucopyranosyl)-; 5'-O-(2-Amino-2-deoxy-β-D-glucosyl)uridine; β-GlcN-Uridine; 2-Amino-2-deoxy-β-D-glucopyranosyl uridine derivative
EINECS	Contact for details

Quality Control

We supply 5'-o-(2-Amino-2-Deoxy-β-D-Glucopyranosyl)-Uridine with a focus on high-purity standards suitable for research and development. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profile is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to prevent degradation. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.