Description

4-Chloro-3-(Trifluoromethyl)Phenacyl Bromide is a high-value, multi-functional organic building block characterized by its reactive phenacyl bromide and halogenated aromatic structure. This compound matters for its versatility as a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals, polymers, and organic semiconductors.
• Chemical Biology Probes: Useful for synthesizing activity-based probes and molecular tags for studying biological processes and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Chloro-3-(Trifluoromethyl)Phenacyl Bromide
CAS No.	630404-09-0
Molecular Formula	C9H5BrClF3O
Molecular Weight	301.49 g/mol
Synonyms	2-Bromo-1-[4-chloro-3-(trifluoromethyl)phenyl]ethanone; 4-Chloro-3-(trifluoromethyl)phenacyl bromide; 2-Bromo-4'-chloro-3'-(trifluoromethyl)acetophenone; α-Bromo-4-chloro-α,α,α-trifluoro-m-acetophenone; 1-(4-Chloro-3-(trifluoromethyl)phenyl)-2-bromoethan-1-one; 4-Chloro-α-bromo-3-(trifluoromethyl)acetophenone; Bromo(4-chloro-3-(trifluoromethyl)phenyl)methanone
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-(Trifluoromethyl)Phenacyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.