Description

Cyclohexanecarbonyl Chloride, 2-Cyano-, (1R,2S)-Rel- (9Ci) is a high-purity, chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of enantiomerically pure pharmaceuticals and agrochemicals, where stereochemical control is critical for efficacy and safety. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in routes requiring the (1R,2S) stereochemistry.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure herbicides, fungicides, and insecticides to enhance selectivity and reduce environmental impact.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development and study of new asymmetric catalytic reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where high stereochemical purity is required.
• Academic & Contract Research: A valuable reagent for synthetic methodology development and target-oriented synthesis in academic and industrial R&D laboratories.

Basic Information

Product Name	Cyclohexanecarbonyl Chloride, 2-Cyano-, (1R,2S)-Rel- (9Ci)
CAS No.	627529-31-1
Molecular Formula	C8H10ClNO
Molecular Weight	171.62 g/mol
Synonyms	(1R,2S)-rel-2-Cyanocyclohexanecarbonyl Chloride; rel-(1R,2S)-2-Cyanocyclohexanecarbonyl Chloride; (1R,2S)-2-Cyanocyclohexanecarboxylic Acid Chloride; 2-Cyano-cyclohexanecarbonyl Chloride, (1R,2S)-rel-; Cyclohexanecarbonyl chloride, 2-cyano-, (1R,2S)-rel-; (1R,2S)-rel-2-Cyano-1-cyclohexanecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of Cyclohexanecarbonyl Chloride, 2-Cyano-, (1R,2S)-Rel- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analysis, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and IR for structural confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.