Description

3-Azabicyclo[3.2.0]Heptane-3-Carbonyl Chloride (9Ci) is a high-purity, reactive bicyclic building block of significant interest in advanced organic synthesis. This compound matters as a key acylating agent and intermediate for constructing complex nitrogen-containing heterocycles, which are privileged scaffolds in modern drug discovery. Pharmaceutical R&D and fine chemical manufacturers need it for the development of novel active pharmaceutical ingredients (APIs), particularly in areas requiring rigid, three-dimensional molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially for central nervous system (CNS) and antiviral targets.
• Agrochemical Synthesis: Used to create advanced, bioactive molecules for crop protection and pest management solutions.
• Peptidomimetic Chemistry: Serves as a constrained scaffold to mimic peptide structures, enhancing metabolic stability and bioavailability.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks.
• Academic and Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in research institutions.
• Custom Synthesis: A starting material for the contract manufacturing of complex, high-value specialty chemicals.

Basic Information

Product Name	3-Azabicyclo[3.2.0]Heptane-3-Carbonyl Chloride (9Ci)
CAS No.	623580-00-7
Molecular Formula	C7H8ClNO
Molecular Weight	157.60 g/mol
Synonyms	3-Carbamoyl-3-azabicyclo[3.2.0]heptane chloride; 3-Azabicyclo[3.2.0]heptane-3-carbonyl chloride; 3-Azabicyclo[3.2.0]heptane-3-carboxylic acid chloride; Bicyclo[3.2.0]heptane-3-carbonyl chloride, 3-aza-; 3-Azabicyclo[3.2.0]heptane-3-carbonyl chloride (9CI); 3-Azabicyclo[3.2.0]heptan-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Azabicyclo[3.2.0]Heptane-3-Carbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.