Description

1H-1,2,4-Triazole-3-Carbonyl Chloride, 5-Amino- (9Ci) is a high-value, multifunctional heterocyclic building block used in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals due to its reactive carbonyl chloride and amino groups. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex triazole-based molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing potential drug candidates, including kinase inhibitors, antifungal agents, and antiviral compounds.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators featuring the 1,2,4-triazole scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of advanced polymers, metal-organic frameworks (MOFs), and functional materials with tailored properties.
• Peptide Mimetics and Bioconjugation: The reactive acid chloride group enables its use in peptide coupling reactions and the creation of bioconjugates for biochemical research.

Basic Information

Item	Details
Product Name	1H-1,2,4-Triazole-3-Carbonyl Chloride, 5-Amino- (9Ci)
CAS No.	619331-69-0
Molecular Formula	C3H3ClN4O
Molecular Weight	146.53 g/mol
Synonyms	5-Amino-1H-1,2,4-triazole-3-carbonyl chloride; 5-Amino-1,2,4-triazole-3-carboxylic acid chloride; 3-Carbonyl chloride-5-amino-1,2,4-triazole; 5-Amino-1H-[1,2,4]triazole-3-carbonyl chloride; 5-Amino-1,2,4-triazole-3-carbonyl chloride; 5-Amino-[1,2,4]triazole-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1H-1,2,4-Triazole-3-Carbonyl Chloride, 5-Amino- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in common polar aprotic solvents (DMF, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.