Description

13-Azido-2,5,8,11-Tetraoxa-Tridecane is a specialized bifunctional PEG derivative featuring a terminal azide group and a reactive hydroxyl group, separated by a tetraethylene glycol spacer. This compound is a crucial building block in click chemistry, enabling efficient, modular, and high-yielding bioconjugation and polymer synthesis under mild conditions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotech, and advanced materials sectors for applications such as drug delivery system development, surface functionalization, and the creation of novel hydrogels and polymers.

Application

• Bioconjugation and Linker Chemistry: Acts as a heterobifunctional crosslinker for attaching biomolecules (e.g., peptides, antibodies, sugars) to surfaces, nanoparticles, or other polymers via azide-alkyne cycloaddition (CuAAC or SPAAC).
• Polymer and Material Science: Serves as a functional monomer or macromonomer for synthesizing azide-functionalized polymers, dendrimers, and smart materials with tailored properties.
• Drug Delivery Systems: Used to create PEGylated drug conjugates or to functionalize liposomes and micelles, enhancing solubility, stability, and targeted delivery of therapeutic agents.
• Surface Modification and Coatings: Enables the "click" immobilization of bioactive molecules onto various substrates (e.g., glass, gold, polymers) for biosensor development, diagnostic assays, and biocompatible coatings.
• Chemical Biology Probes: Facilitates the labeling and tracking of biomolecules in live cells or complex biological systems for research and diagnostic purposes.
• Hydrogel Formation: Participates in cross-linking reactions to form biocompatible hydrogels for tissue engineering, 3D cell culture, and controlled release applications.

Basic Information

Product Name	13-Azido-2,5,8,11-Tetraoxa-Tridecane
CAS No.	606130-90-9
Molecular Formula	C11H23N3O4
Molecular Weight	261.32 g/mol
Synonyms	Azido-PEG4-OH; 11-Azido-3,6,9-trioxaundecan-1-ol; 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethanol; 3,6,9,12-Tetraoxapentadecan-15-ol, 14-azido-; Azido tetraethylene glycol; N3-PEG4-OH; Azido-PEG4-alcohol; 14-Azido-3,6,9,12-tetraoxapentadecan-1-ol
EINECS	Contact for details

Quality Control

Our 13-Azido-2,5,8,11-Tetraoxa-Tridecane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the presence of the azide functional group, avoid contact with heavy metals and strong reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.