Description

3α,7α,11α-Tris(Acetyloxy)-12-Oxo-5β-Cholan-24-Oic Acid Methyl Ester is a key cholanic acid derivative, serving as a critical synthetic intermediate in the production of advanced pharmaceutical compounds. Its value lies in providing a functionalized steroid backbone essential for developing targeted therapeutic agents with specific biological activity. This high-purity intermediate is primarily needed by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel bile acid analogs, hormone derivatives, and other specialized steroidal molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel steroidal drugs and therapeutic agents.
• Research & Development: Used in academic and industrial laboratories for investigating bile acid metabolism and developing new chemical entities.
• Steroid Chemistry: Serves as a versatile precursor for the preparation of modified cholic acid derivatives and other complex steroid frameworks.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Probes: Employed in the development of probes to study receptor interactions and enzymatic pathways involving bile acids.

Basic Information

Product Name	3α,7α,11α-Tris(Acetyloxy)-12-Oxo-5β-Cholan-24-Oic Acid Methyl Ester
CAS No.	69889-92-5
Molecular Formula	C₃₁H₄₆O₈
Molecular Weight	546.70 g/mol
Synonyms	Methyl 3α,7α,11α-triacetoxy-12-oxo-5β-cholan-24-oate; 12-Oxo-3α,7α,11α-triacetoxy-5β-cholan-24-oic Acid Methyl Ester; 3α,7α,11α-Triacetoxy-12-oxo-5β-cholan-24-oic Acid Methyl Ester; Methyl 3α,7α,11α-triacetyloxy-12-oxo-5β-cholan-24-oate; 12-Ketolithocholic Acid Methyl Ester Triacetate; Cholan-24-oic Acid Derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3α,7α,11α-Tris(Acetyloxy)-12-Oxo-5β-Cholan-24-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high chemical purity and structural identity, meeting the exacting standards required for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.