Description

Bicyclo[2.2.2]Octane-2-Carbonyl Chloride, 1,6-Dimethyl-5-Oxo-, (1Alpha,2Beta,4Alpha)- (9Ci) is a highly functionalized bicyclic acid chloride derivative, serving as a critical chiral building block in advanced organic synthesis. Its rigid, three-dimensional bicyclo[2.2.2]octane scaffold and reactive carbonyl chloride group make it invaluable for introducing complex, sterically defined molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel drug candidates, particularly those targeting the central nervous system (CNS) or requiring specific three-dimensional pharmacophores.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the bicyclic structure can contribute to unique biological activity and environmental stability.
• Material Science Research: Acts as a precursor for specialty polymers, dendrimers, or metal-organic frameworks (MOFs) requiring precise geometric control.
• Asymmetric Catalysis Ligand Precursor: Employed in the synthesis of novel chiral ligands and organocatalysts for enantioselective transformations.
• Chemical Biology Probe Development: Useful for creating activity-based probes or affinity tags to study enzyme function and protein interactions.
• Academic & R&D: A valuable tool in academic laboratories for methodological studies in stereoselective synthesis and the construction of complex polycyclic systems.

Basic Information

Product Name	Bicyclo[2.2.2]Octane-2-Carbonyl Chloride, 1,6-Dimethyl-5-Oxo-, (1Alpha,2Beta,4Alpha)- (9Ci)
CAS No.	69857-64-3
Molecular Formula	C11H15ClO2
Molecular Weight	214.69 g/mol
Synonyms	(1α,2β,4α)-1,6-Dimethyl-5-oxobicyclo[2.2.2]octane-2-carbonyl chloride; 1,6-Dimethyl-5-oxobicyclo[2.2.2]octane-2-carbonyl chloride, (1α,2β,4α)-; Bicyclo[2.2.2]octane-2-carbonyl chloride, 1,6-dimethyl-5-oxo-, (1α,2β,4α)-; 69857-64-3; (1alpha,2beta,4alpha)-1,6-Dimethyl-5-oxobicyclo[2.2.2]octane-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.2]Octane-2-Carbonyl Chloride, 1,6-Dimethyl-5-Oxo-, (1Alpha,2Beta,4Alpha)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Solubility	Soluble in common organic solvents (e.g., DCM, THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.