Description

1H-Imidazole-4-Carboxylic Acid, 5-(Chlorocarbonyl)- (9Ci) is a high-purity, reactive chemical intermediate featuring both a carboxylic acid and an acid chloride functional group on the imidazole heterocycle. This unique bifunctional structure makes it a critical building block for the synthesis of complex molecules, enabling the creation of novel compounds with tailored properties. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and metabolic diseases.
• Agrochemical Synthesis: Used to construct novel fungicides, herbicides, and plant growth regulators by introducing the imidazole pharmacophore.
• Ligand and Chelator Development: Serves as a starting material for creating specialized ligands used in catalysis and metal ion chelation.
• Polymer and Material Science: Incorporated into polymer backbones or as a surface modifier to impart specific chemical functionality or biocompatibility to advanced materials.
• Peptide Mimetics and Bioconjugation: The reactive acid chloride group is utilized for coupling reactions to create peptide-like structures or for bioconjugation applications.
• Research & Development: Essential for medicinal chemistry programs and academic research exploring new chemical entities and reaction pathways.

Basic Information

Product Name	1H-Imidazole-4-Carboxylic Acid, 5-(Chlorocarbonyl)- (9Ci)
CAS No.	69579-33-5
Molecular Formula	C5H3ClN2O3
Molecular Weight	174.54 g/mol
Synonyms	5-(Chlorocarbonyl)-1H-imidazole-4-carboxylic acid; Imidazole-4,5-dicarboxylic acid 5-chloride; 4-Carboxyimidazole-5-carbonyl chloride; 1H-Imidazole-4,5-dicarboxylic acid 5-chloride; 5-Carboxyimidazole-4-carbonyl chloride; Imidazole-4,5-dicarboxylic acid monoacid chloride
EINECS	Contact for details

Quality Control

Our production of 1H-Imidazole-4-Carboxylic Acid, 5-(Chlorocarbonyl)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for research and industrial use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis of the acid chloride group. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.