Description

(2R,3R,4S,5R)-2-(2-Amino-1,7-Dimethyl-6-Oxopurin-9-Ium-9-Yl)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-3-Olate is a high-purity, modified nucleoside derivative with significant relevance in advanced pharmaceutical research and development. This compound serves as a critical building block and reference standard for the synthesis and study of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on nucleotide-based therapies and molecular biology applications.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel nucleoside analog drugs targeting viral infections and cancer.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, metabolic pathway analysis, and molecular biology research.
• Antiviral Drug Development: Serves as a core scaffold for designing and testing new antiviral compounds, particularly against DNA viruses.
• Oncology Research: Investigated for its potential incorporation into chemotherapeutic agents that interfere with DNA synthesis in rapidly dividing cells.
• Diagnostic Reagent Manufacturing: Employed in the production of specialized reagents and kits for genetic testing and molecular diagnostics.
• Academic Research: Utilized in university and institutional labs for studying nucleotide chemistry, enzyme mechanisms, and nucleic acid metabolism.

Basic Information

Product Name	(2R,3R,4S,5R)-2-(2-Amino-1,7-Dimethyl-6-Oxopurin-9-Ium-9-Yl)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-3-Olate
CAS No.	69453-64-1
Molecular Formula	C13H17N5O5
Molecular Weight	323.31 g/mol
Synonyms	9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-2-amino-1,7-dimethyl-6-oxo-6,9-dihydro-1H-purin-9-ium-3-olate; 2-Amino-1,7-dimethyl-6-oxopurine riboside derivative; Modified Adenosine Analog; 1,7-Dimethylisoguanosine derivative; 6-Oxo-2-aminopurine nucleoside; 69453-64-1; (2R,3R,4S,5R)-2-(2-Amino-1,7-dimethyl-6-oxo-1,6-dihydro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
EINECS	Contact for details

Quality Control

Our (2R,3R,4S,5R)-2-(2-Amino-1,7-Dimethyl-6-Oxopurin-9-Ium-9-Yl)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-3-Olate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.