Description

3-(6-Amino-8-Mercapto-Purin-9-Yl)-Propane-1,2-Diol is a high-purity, modified purine derivative of significant interest in advanced pharmaceutical and biochemical research. This compound serves as a critical building block for the synthesis of novel nucleoside analogs and enzyme inhibitors, offering a versatile scaffold for drug discovery. It is primarily utilized by research institutions and pharmaceutical companies focused on developing targeted therapies, particularly in the fields of oncology and virology.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel purine-based nucleoside analogs for antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate purine metabolism pathways and related biological mechanisms.
• Proteomics & Molecular Biology: Employed in the development of probes and tools for studying protein-nucleic acid interactions and signal transduction.
• Chemical Synthesis: Serves as a versatile starting material for the preparation of more complex, functionalized heterocyclic compounds.
• Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and organic synthesis.

Basic Information

Product Name	3-(6-Amino-8-Mercapto-Purin-9-Yl)-Propane-1,2-Diol
CAS No.	69400-33-5
Molecular Formula	C9H11N5O2S
Molecular Weight	253.28 g/mol
Synonyms	6-Amino-9-(1,2-dihydroxypropyl)-8-mercaptopurine; 8-Thio-6-aminopurine-9-propane-1,2-diol; 9-(1,2-Dihydroxypropyl)-6-amino-8-mercaptopurine; 6-Amino-8-mercapto-9-(1,2-dihydroxypropyl)purine; 3-(6-Amino-8-mercapto-9H-purin-9-yl)propane-1,2-diol; 8-Mercapto-6-aminopurine-9-propane-1,2-diol; 6-Amino-8-thiopurine-9-propane-1,2-diol
EINECS	Contact for details

Quality Control

Our 3-(6-Amino-8-Mercapto-Purin-9-Yl)-Propane-1,2-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.