Description

3'-Deoxycytidine 5'-Triphosphate (CAS NO 69383-05-7) is a modified nucleoside triphosphate analog crucial for advanced biochemical research and development. This compound serves as a vital building block and substrate in enzymatic studies, particularly where chain termination or specific structural modifications are required. It is primarily utilized by researchers and manufacturers in the fields of molecular biology, enzymology, and pharmaceutical development for applications such as nucleic acid synthesis and mechanistic investigations.

Application

• Substrate for DNA/RNA Polymerases: Used in enzymatic synthesis and studies of nucleic acid replication and transcription mechanisms.
• Chain Terminator in Sequencing: Acts as a controlled terminator in classic Sanger sequencing or related analytical techniques.
• Biochemical Research Reagent: Essential for investigating enzyme kinetics, substrate specificity, and inhibition studies of polymerases and kinases.
• Synthesis of Modified Oligonucleotides: Incorporated into oligonucleotides to create probes or primers with specific properties for diagnostic or therapeutic research.
• Antiviral and Anticancer Research: Studied as a potential metabolite or active form of nucleoside analog prodrugs in medicinal chemistry programs.
• Metabolic Pathway Studies: Employed to trace or modulate nucleotide metabolism in cellular systems.

Basic Information

Product Name	3'-Deoxycytidine 5'-Triphosphate
CAS No.	69383-05-7
Molecular Formula	C9H16N3O13P3
Molecular Weight	491.15 g/mol
Synonyms	3'-Deoxy-CTP; Cordycepin 5'-triphosphate cytidine derivative; 2'-Deoxycytidine 5'-triphosphate (common misnomer, verify structure); dCytidine 5'-triphosphate analog; 3'-dCTP; Cytidine 5'-(tetrahydrogen triphosphate), 3'-deoxy-; (2'R,3'S,5'R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxy-4-(phosphonooxy)tetrahydrofuran-2-yl methyl trihydrogen triphosphate
EINECS	Contact for details

Quality Control

Our 3'-Deoxycytidine 5'-Triphosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
Assay (Enzymatic/Spectrophotometric)	≥ 90%
Water Content (Karl Fischer)	≤ 5%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.