Description

Bicyclo[3.3.1]Nonane-2-Carbonyl Chloride, Endo- (9Ci) is a specialized bicyclic acid chloride derivative, serving as a critical high-purity building block in advanced organic synthesis. Its unique sterically hindered, endo-configured bicyclic framework makes it an invaluable precursor for constructing complex molecular architectures with defined three-dimensional geometry. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to introduce the bicyclo[3.3.1]nonane scaffold, a motif known for influencing bioavailability and material properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those requiring rigid, three-dimensional carbon frameworks to modulate receptor binding and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the bicyclic structure can contribute to unique biological activity and environmental persistence profiles.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts in asymmetric synthesis, leveraging its defined stereochemistry.
• Advanced Material Monomers: Employed in the synthesis of specialty polymers and dendrimers with tailored thermal and mechanical properties for high-performance applications.
• Chemical Biology Probes: Utilized to create molecular probes and tags for studying biological systems, benefiting from its ability to be functionalized and its potential for lipophilicity.
• Academic and R&D Laboratories: Fundamental building block in methodological organic chemistry research for exploring new synthetic routes and reaction mechanisms.

Basic Information

Product Name	Bicyclo[3.3.1]Nonane-2-Carbonyl Chloride, Endo- (9Ci)
CAS No.	69205-20-5
Molecular Formula	C10H13ClO
Molecular Weight	184.66 g/mol
Synonyms	Endo-Bicyclo[3.3.1]nonane-2-carbonyl chloride; 2-Endo-Bicyclo[3.3.1]nonanecarbonyl chloride; Bicyclo[3.3.1]nonane-2-carbonyl chloride, endo-; 2-Carboxybicyclo[3.3.1]nonane, 2-chlorocarbonyl-, endo-; endo-2-Chlorocarbonylbicyclo[3.3.1]nonane; endo-Norbornane-2-carbonyl chloride (related structural analog); Bicyclo[3.3.1]nonane-2-carboxylic acid chloride, endo-
EINECS	Contact for details

Quality Control

Our Bicyclo[3.3.1]Nonane-2-Carbonyl Chloride, Endo- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. Product quality is verified through a comprehensive suite of analytical techniques including NMR, HPLC, and GC. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment. We support compliance with relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%
Isomeric Purity (endo-)	≥ 98%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.