Description

1-β-Arabinofuranosyl-5-Propyluracil-5'-Triphosphate is a modified nucleoside triphosphate analog, a critical building block for advanced biochemical research and pharmaceutical development. Its primary value lies in its ability to act as a substrate or inhibitor for DNA/RNA polymerases and other enzymes, enabling studies in virology, enzymology, and targeted drug discovery. This high-purity biochemical is essential for researchers and manufacturers in antiviral drug development, molecular biology, and nucleotide-based therapeutic applications, where precise molecular structure and activity are paramount.

Application

• Antiviral Research & Drug Development: Used as a substrate analog to study and inhibit viral polymerases (e.g., Hepatitis B Virus, Herpesviruses).
• Enzymology Studies: Serves as a critical tool for investigating the kinetics and mechanisms of DNA/RNA polymerases and kinases.
• Nucleotide-Based Probe Synthesis: Incorporated into oligonucleotides for creating labeled probes used in diagnostics and genomic research.
• Biochemical Assay Development: Employed in high-throughput screening (HTS) assays to identify novel enzyme inhibitors.
• Metabolic Pathway Analysis: Used to trace and understand nucleotide salvage and anabolic pathways in cellular systems.
• Preparation of Custom Nucleotide Libraries: A key raw material for synthesizing specialized nucleotide libraries for next-generation sequencing applications.

Basic Information

Product Name	1-β-Arabinofuranosyl-5-Propyluracil-5'-Triphosphate
CAS No.	69175-42-4
Molecular Formula	C₁₅H₂₃N₂O₁₆P₃
Molecular Weight	604.27 g/mol
Synonyms	5-Propyl-araUTP; 1-β-D-Arabinofuranosyl-5-propyluracil 5'-triphosphate; Ara-5-propylUTP; 5-Propyl-1-β-D-arabinofuranosyluracil triphosphate; 5-Propyl-arabinosyluracil triphosphate; BV-araU TP; BVaraUTP; 5-Propyl-β-D-arabinofuranosyluracil 5'-triphosphate
EINECS	Contact for details

Quality Control

Our 1-β-Arabinofuranosyl-5-Propyluracil-5'-Triphosphate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality control protocols are designed to meet the stringent requirements of pharmaceutical and life science customers.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the product desiccated and under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (UV)	≥ 90% (anhydrous basis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.