Description

5-(3,3,3-Trifluoro-1-Propenyl)-2'-Deoxyuridylate is a specialized fluorinated nucleoside analog, a key building block in advanced pharmaceutical and biochemical research. Its unique structure, featuring a trifluoropropenyl group, makes it a critical intermediate for developing novel antiviral and anticancer agents, particularly in the synthesis of modified oligonucleotides. This high-purity compound is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on next-generation therapeutic discovery.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antiviral and antineoplastic (anticancer) nucleoside analogs.
• Biochemical Research: Used as a modified nucleotide building block for studying enzyme mechanisms, DNA/RNA interactions, and metabolic pathways.
• Antiviral Drug Development: Serves as a key scaffold in the research and development of therapeutics targeting viral polymerases.
• Proteomics & Genomics: Employed in the creation of labeled probes and tools for diagnostic assays and molecular biology studies.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for high-value, low-volume specialty chemicals.
• Academic Research: Fundamental research tool in university and institutional labs exploring fluorinated biomolecules and their properties.

Basic Information

Product Name	5-(3,3,3-Trifluoro-1-Propenyl)-2'-Deoxyuridylate
CAS No.	69150-50-1
Molecular Formula	C13H14F3N2O8P
Molecular Weight	414.23 g/mol
Synonyms	5-(3,3,3-Trifluoro-1-propenyl)-2'-deoxyuridine 5'-(dihydrogen phosphate); 5-Trifluoropropenyl-2'-deoxyuridylate; 5-(3,3,3-Trifluoroallyl)-2'-deoxyuridine 5'-monophosphate; 2'-Deoxy-5-(3,3,3-trifluoro-1-propen-1-yl)uridine 5'-monophosphate; 5-(Trifluoroprop-1-en-1-yl)-2'-deoxyuridylate; F3C-CH=CH-dUMP; Trifluoropropenyl-dUMP
EINECS	Contact for details

Quality Control

Our 5-(3,3,3-Trifluoro-1-Propenyl)-2'-Deoxyuridylate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical R&D, and we can support custom synthesis to meet specific project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.