Description

5α-Cholest-8(14)-Ene-3β,7α,15α-Triol Triacetate is a high-purity, semi-synthetic steroidal derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate or reference standard for the study of cholesterol metabolism and the synthesis of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of therapeutic agents targeting metabolic and endocrine pathways. The product, identified by CAS number 69140-10-9, is supplied under stringent quality controls to ensure consistency for sensitive applications.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroidal drugs and investigational compounds.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to steroidogenesis and cholesterol biosynthesis pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Metabolic Pathway Studies: Employed in cellular and in vitro assays to investigate the biological activity and metabolism of oxysterols and related sterols.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic chemistry, medicinal chemistry, and biochemistry.

Basic Information

Item	Detail
Product Name	5α-Cholest-8(14)-Ene-3β,7α,15α-Triol Triacetate
CAS No.	69140-10-9
Molecular Formula	C₃₃H₅₂O₆
Molecular Weight	544.77 g/mol
Synonyms	5α-Cholest-8(14)-ene-3β,7α,15α-triol, 3,7,15-triacetate; (3β,7α,15α)-5α-Cholest-8(14)-ene-3,7,15-triol Triacetate; 3β,7α,15α-Triacetoxy-5α-cholest-8(14)-ene; 7α,15α-Diacetoxy-3β-hydroxy-5α-cholest-8(14)-ene 3-acetate; Cholestane Triol Triacetate Derivative
EINECS	Contact for details

Quality Control

Our 5α-Cholest-8(14)-Ene-3β,7α,15α-Triol Triacetate is manufactured and handled under a quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Standard testing includes chromatographic purity analysis (HPLC), identity confirmation (IR, NMR), and specific rotation. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.