Description

5α-Cholest-8(14)-Ene-3β,15β-Diol Diacetate is a high-purity steroidal diacetate derivative, serving as a critical advanced intermediate in pharmaceutical research and synthesis. This compound is valued for its defined stereochemistry and high chemical purity, which are essential for ensuring the consistency and efficacy of downstream active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents and complex organic syntheses.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroid-based drugs and bioactive molecules.
• Research & Development: Used as a reference standard or starting material in medicinal chemistry for exploring new therapeutic pathways.
• Process Chemistry: Employed in scale-up and optimization studies for the production of steroidal APIs under Good Manufacturing Practice (GMP) conditions.
• Biochemical Research: Investigated for its biological activity and potential interactions with enzymes or receptors in metabolic studies.
• Fine Chemical Synthesis: Serves as a versatile chiral synthon for constructing more complex molecular architectures in organic chemistry.

Basic Information

Product Name	5α-Cholest-8(14)-Ene-3β,15β-Diol Diacetate
CAS No.	69140-09-6
Molecular Formula	C₃₁H₅₀O₄
Molecular Weight	486.73 g/mol
Synonyms	3β,15β-Diacetoxy-5α-cholest-8(14)-ene; 5α-Cholest-8(14)-ene-3β,15β-diol 3,15-diacetate; 3β,15β-Dihydroxy-5α-cholest-8(14)-ene diacetate; Cholestadienediol Diacetate; (3β,5α,15β)-Cholest-8(14)-ene-3,15-diol 3,15-diacetate; 15β-Acetoxy-3β-acetoxy-5α-cholest-8(14)-ene
EINECS	Contact for details

Quality Control

Our 5α-Cholest-8(14)-Ene-3β,15β-Diol Diacetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by advanced analytical techniques like HPLC and NMR. We support custom synthesis and can tailor specifications to meet specific research or cGMP-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term stability is required, and appropriate personal protective equipment should be used when handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solvent Residues (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.