Description

Methyl 2-(Fluoroformyl)difluoroacetate is a highly reactive fluorinated building block and acylating agent, essential for introducing the difluoroacetate moiety into complex molecular architectures. Its core value lies in enabling precise fluorination, a critical step for modulating the physicochemical and metabolic properties of target compounds in advanced research and development. This specialty chemical is primarily needed by pharmaceutical, agrochemical, and advanced material scientists for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), including protease inhibitors and other therapeutics where fluorination enhances bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the difluoroacetate group contributes to improved efficacy and environmental profile.
• Fluorinated Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and electronic materials with enhanced chemical resistance and unique surface properties.
• Organic Synthesis Reagent: Acts as a versatile acylating and fluorinating agent in research-scale organic chemistry for constructing complex molecules in medicinal chemistry and material science projects.
• Liquid Crystal & Display Technology: Potential intermediate in the synthesis of fluorinated liquid crystals used in high-performance displays.

Basic Information

Product Name	Methyl 2-(Fluoroformyl)difluoroacetate
CAS No.	69116-71-8
Molecular Formula	C4H3F3O3
Molecular Weight	156.06 g/mol
Synonyms	Methyl Difluoro(fluoroformyl)acetate; Difluoro(fluoroformyl)acetic Acid Methyl Ester; Methyl 2-Difluoro(fluoroformyl)acetate; 2-(Fluoroformyl)-2,2-difluoroacetic Acid Methyl Ester; Methyl 2,2-Difluoro-2-(fluoroformyl)acetate; Fluorocarbon Ester; Acetic acid, difluoro(fluoroformyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(Fluoroformyl)difluoroacetate adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at recommended temperatures (typically 2-8°C or as specified). This material is hygroscopic (moisture-sensitive) and highly volatile. Keep away from heat, sparks, open flames, and strong acids/bases. Use under an inert atmosphere for prolonged storage to maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.