Description

5-(1-Methoxyethyl)Uridine is a modified nucleoside building block of significant interest in advanced pharmaceutical and biochemical research. Its unique structure, featuring a methoxyethyl group at the 5-position of the uridine base, makes it a valuable precursor for the synthesis of oligonucleotides and nucleotide analogs. This compound is primarily utilized by researchers and manufacturers in the fields of antiviral drug development, mRNA technology, and proteomics.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside-based antiviral and anticancer therapeutics.
• Oligonucleotide Synthesis: Used in solid-phase synthesis to incorporate modified bases into DNA/RNA strands for research and therapeutic applications (e.g., antisense oligonucleotides, siRNA).
• Proteomics & Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to investigate nucleic acid metabolism and related pathways.
• mRNA Vaccine & Therapy Development: Potential use in creating modified mRNA constructs to enhance stability and translational efficiency.
• Diagnostic Reagent Manufacturing: Component in the production of probes and primers for molecular diagnostics.

Basic Information

Product Name	5-(1-Methoxyethyl)Uridine
CAS No.	68972-46-3
Molecular Formula	C12H18N2O7
Molecular Weight	302.28 g/mol
Synonyms	1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(1-methoxyethyl)pyrimidine-2,4-dione; 5-(1-Methoxyethyl)uridine; Uridine, 5-(1-methoxyethyl)-; 5-(α-Methoxyethyl)uridine
EINECS	Contact for details

Quality Control

Our 5-(1-Methoxyethyl)Uridine is produced under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research and cGMP manufacturing. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant ICH guidelines and can support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.